EZH2
The rats with decreased EZH2 expression indeed decreased their compulsivity!
The rats which received the knock down virus (EZH2 KD) display lower alcohol consumption than the ones which received an inactive virus (Scrambled virus, SCR).
PKCδ+ neurons
PKCδ+ neurons deletion did not seem to affect alcohol consumption despite negative consequences.
The rats displayed alcohol consumption as they were doing before surgeries, regardless the treatment they received.
For the implications and conclusions that these results suggest, please click here!